Publications

Featured Articles

Functionalizing Hydrogel Nanovials with Vesicles Mimicking Antigen-Presenting Vesicles and Cancer Exosomes Improves T Cell Capture and Activation.

Blade A. Olson, Michael Mellody, Citradewi Soemardy, Zhiyuan Mao, Anna Mei, Katie Lippert, Magnus A. G. Hoffmann, Dino Di Carlo, Stephen L. Mayo

ACS Nano, July 2026

Mapping and engineering the human cell–cell interactome

Dino Di Carlo, Leonardo Morsut, Megan L. McCain, Heather J. Wright, Mohamad Abedi, Sean A. Yamada-Hunter, Jason Z. Zhang, Keriann Backus, Eunji Chung, Yingxiao Wang, Thomas A. Rando, Long Cai, Matt Thomson, Michael B. Elowitz, John K. Lee & Owen Witte

Nature Biotechnology, June 2026

Cell-Cell-Seq resolves contact-associated NK cell activation in defined tumor cell dyads

Jesse Liang, Devon Shao, Dino Di Carlo, Joseph de Rutte

bioRxiv, June 2026

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Antibody Discovery and IgG Profiling

Cell Line Development

Joseph de Rutte 5/1/26 Joseph de Rutte 5/1/26

Universal Nanovial Screening Enables Functional Discovery of Metabolite-Reactive T‑Cell Receptors for Cancer Therapy

Citradewi Soemardy, Yan-Ruide Li, Yichen Zhu, Xinyuan Shen, Lili Yang, Dino Di Carlo

ACS Nano, April 2026

Joseph de Rutte 5/22/25 Joseph de Rutte 5/22/25

Linking Epitope-Specific T-Cell Receptors to IFNγ Secretion Using Nanovial Technology

Jet van den Dijssel, Tejas Menon, Hayley A. McQuilten, Oliver Eltherington, Alexis Gonzalez, Sevana Baghdasarian, Citradewi Soemardy, Dino Di Carlo, Klaas P.J.M. van Gisbergen, Anja ten Brinke, Carolien E. van de Sandt

European Journal of Immunology, May 2025

Joseph de Rutte 4/16/24 Joseph de Rutte 4/16/24

Defining T cell receptor repertoires using nanovial-based binding and functional screening

Doyeon Koo, Zhiyuan Mao, Robert Dimatteo, Miyako Noguchi, Natalie Tsubamoto, Jami McLaughlin, Wendy Tran, Sohyung Lee, Donghui Cheng, Joseph de Rutte, Giselle Burton Sojo, Owen N. Witte & Dino Di Carlo

PNAS, March 2024