Immunology
Connect Immune Recognition To Functional Response
Markers Identify Immune Cells. Secretions reveal response.
Immune responses are shaped by what cells recognize, how they activate, what they secrete, how they kill or suppress, and how they communicate with other cells. But many workflows still separate identity, specificity, and function. Nanovials bring secreted immune function into a sortable, recoverable format, helping researchers connect immune cell identity with antigen recognition and functional response.
A sortable single-cell immunoassay for immune function
A familiar antibody-sandwich immunoassay format, analyzed by flow cytometry, so secretion readouts can be combined with the FACS markers, viability dyes, and gating strategies you already use.
How it works
Interrogate the immune responses that matter most
Vaccine response and antigen presentation
Pair APCs and T cells to profile antigen presentation, antigen-specific activation, and vaccine-relevant immune responses.
B cell function and antibody discovery
Identify antibody-secreting cells and recover functional clones based on secretion level and antigen-specific binding.
T cell activation and cytokine secretion
Measure secreted cytokines from viable T cells after antigen-specific or polyclonal stimulation, alongside immunophenotyping and activation markers.
Immune cell-target cell interactions and engagers
Co-localize immune cells with target cells to study interaction-driven biology, including tumor-T cell interactions, NK-target interactions, and T cell engager assays.
Antigen-specific T cell and TCR discovery
Prioritize T cells by antigen recognition and secreted function, then recover cells for receptor sequencing or downstream validation.
CAR-T and engineered T cell screening
Compare engineered T cell candidates by secretion output, target-dependent response, inflammatory cytokine profiles.
Featured Resources
Protocols, guides, applications, and key publications.
Find the right Nanovial workflow for your immune assay
Developer kits for
Single-Cell Secretion Assays
Build single-cell secretion assays to profile cytokines, antibodies, or other secreted immune signals from viable cells.
Developer kits for
Multicell Interaction Assays
Co-localize immune cells with target cells or antigen-presenting cells to study interaction-driven biology in defined cell pairs.
Antibody Discovery Kits
Screen and recover antibody-secreting cells based on secreted antibody signal or antigen-specific binding.