Publications

Featured Articles

Functionalizing Hydrogel Nanovials with Vesicles Mimicking Antigen-Presenting Vesicles and Cancer Exosomes Improves T Cell Capture and Activation.

Blade A. Olson, Michael Mellody, Citradewi Soemardy, Zhiyuan Mao, Anna Mei, Katie Lippert, Magnus A. G. Hoffmann, Dino Di Carlo, Stephen L. Mayo

ACS Nano, July 2026

Mapping and engineering the human cell–cell interactome

Dino Di Carlo, Leonardo Morsut, Megan L. McCain, Heather J. Wright, Mohamad Abedi, Sean A. Yamada-Hunter, Jason Z. Zhang, Keriann Backus, Eunji Chung, Yingxiao Wang, Thomas A. Rando, Long Cai, Matt Thomson, Michael B. Elowitz, John K. Lee & Owen Witte

Nature Biotechnology, June 2026

Cell-Cell-Seq resolves contact-associated NK cell activation in defined tumor cell dyads

Jesse Liang, Devon Shao, Dino Di Carlo, Joseph de Rutte

bioRxiv, June 2026

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Antibody Discovery and IgG Profiling

Cell Line Development

Joseph de Rutte 7/5/25 Joseph de Rutte 7/5/25

Screening of a pooled library of chimeric antigen receptor T cells based on secretory function

Citradewi Soemardy, Anna Mei, Rocio Castellanos-Rueda, Nikol Garcia Espinoza, Monika Kizerwetter, Jamie B Spangler, Sai T Reddy, Dino Di Carlo

bioRxiv, July 2025

Joseph de Rutte 6/20/25 Joseph de Rutte 6/20/25

Specific Stimulation and Multiplex Secretion Analysis of T Cells Using a Suspendable Hydrogel Platform Enables Immunophenotyping at the Single-Cell Scale

Monika Kizerwetter, Doyeon Koo, Citradewi Soemardy, Théo Nass, Joseph Choy, Ariel Isser, Nikol Garcia Espinoza, Aleksander Geske, Xinzhong Dong, Jonathan P. Schneck, Dino Di Carlo, Jamie B. Spangler

ACS Nano, June 2025

Joseph de Rutte 5/22/25 Joseph de Rutte 5/22/25

Linking Epitope-Specific T-Cell Receptors to IFNγ Secretion Using Nanovial Technology

Jet van den Dijssel, Tejas Menon, Hayley A. McQuilten, Oliver Eltherington, Alexis Gonzalez, Sevana Baghdasarian, Citradewi Soemardy, Dino Di Carlo, Klaas P.J.M. van Gisbergen, Anja ten Brinke, Carolien E. van de Sandt

European Journal of Immunology, May 2025