Published in ACS Nano: Recent Advances in Lab-on-a-particle Technology Unlocks Simplified Workflows for Single-cell Research
Nanovials are microparticles with cavities that act as miniature test tubes for single cells, storing information about the cell's functions (e.g. secreted products) on their surfaces, and analyzed by instruments already in labs, like flow cytometers.
This new nanovial formulation, with local gelatin functionalized in the cavity achieves: (1) improved loading of single cells beating Poisson loading limits, and (2) an emulsion-free workflow with reduced cross-talk of secreted antibodies. The nanovials are sorted using standard fluorescence activated cell sorters (e.g. the Sony SH800 in this work).
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More information on the study published in ACS Nano can be found here.
About Partillion Bioscience
Partillion Bioscience is venture-backed life science company developing a next generation single-cell analysis platform. Our award winning nanovial technology enables our customers to accelerate therapeutic development to address the most difficult diseases and provide advanced scientific insights. Our reagent-based platform unlocks the ability to screen hundreds of thousands to millions of individual cells based on critical yet difficult to probe functional information all while using common lab equipment.