Biotinylated Nanovials

Unlock a world of possibility with flexible formats

Each Nanovial acts as an individual cell chamber.

Reach unparalleled throughput with millions of Nanovials in a test tube.

Flexibility and Customization

Original Formulation

EZM Nanovials

  • Biotinylated, for easy modification

  • Low autofluorescence, great for complex fluorophore panels.

  • Biotinylated, for easy modification

  • New formulation with cavity-localized extracellular matrix.

  • Ideal for adherent cells, improved cell recovery, and high-secreting cells.

35 µm

50 µm

Different Nanovial sizes for diverse cell types and applications

Uncomplicated Workflows

Use the antibodies, antigens, or pMHCs you already have to build a custom single-cell secretion assay

No Black Box

Easy visualization so you can monitor your workflows

FAQs

  • Nanovials contain cavities just a bit larger than the size of a cell. Cells are loaded into a large population of Nanovials to ensure a single-cell behavior.

  • Cross-talk is addressed in multiple ways

    1. Before loading, cells are washed to remove any secretions in the cell suspension.

    2. Cells are loaded with a large ratio of Nanovials, the possibility of two cells in close proximity is decreased.

    3. Our EZM formulation has biotin groups localized to the cavity which reduces cross-talk from neighboring cells.

    4. Secretion incubation time can be optimized for your cells of interest. For high secreting cells, 30-60 minutes was found to work well in our hands.

  • Bulk and custom orders may be available upon request. Meet with one of our team members to discuss your project today.

Ready to get started?